Gregory Petsko quote ✍️

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Alzheimer's disease starts when a protein that should be folded up properly misfolds into a kind of demented origami.

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Sickness – Sartre’s first novel
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Hint 1 meaning
Seasickness; hence, any similar sickness of the stomach accompanied with a propensity to vomit; qualm; squeamishness of the stomach; loathing.
Hint 2 anagram
NUEASA
Hint 3 another clue
PERPLEXED state
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