Crossword-Solution: HYPOTHYROIDISM 14 letters, 1 clue 🏆 scrabble score: 31

The stimulating effect of thyroid secretion on growth and metabolism, shown both experimentally and clinically in the therapeutic triumphs of thyroid treatment in myxoedema and hypothyroidism, seems to justify the view that failure of thyroid function plays an important part in reducing the capacity for multiplication and regeneration of cells.

Between the manifestations of hypothyroidism and those of old age there are undoubtedly striking resemblances, such as the dry skin, the loss of hair, the diminished mental and bodily energy, and the increased amount of interstitial fibrous tissue.

Thompson, in the Royal Hospital, Chelsea, with baldness and a grey beard, was given thyroid extract, as he was thought to have hypothyroidism; his general condition then improved wonderfully, and his scalp became covered with dark brown hair which had to be cut at intervals.

There is hypertrophy of the thyroid gland or at least signs of hypothyroidism, general hypertrophy of glands, disturbance of heart rhythm, and nervous symptoms.

With regard to treatment, according to Castellani and Chalmers the indications are the same as those for African trypanosomiasis, together with treatment for hypothyroidism.